| Satyevikrama | Truth makes him powerful |
| Saubhagh | One who is very fortunate. |
| Sauhridh | A person with a good heart. |
| Saumithra | Lord Lakshman son of Sumitra) |
| Sauvar | Belonging to sound, A musical note |
| Savant | A learned and wise scholar. |
| Savya Sachi | Another name of Arjun, Ambidextrous |
| Savyamoonth | Savyamoonth comes from An Indian word meaning, Defender of people |
| Savyashachee | Ambidextrous while shooting |
| Sayshanth | Avatar of Lord Vishnu, Good peace |
| Selva Kumar | A wealthy and prosperous young prince. |
| Selvanathn | Selvanathn means 'Gift of the Lord' or 'Divine Gift' in Sanskrit, a combination of Selva (Lord) and Nathn (Gift). |
| Selvian | Of or pertaining to Selvians, a people or tribe, possibly from the Latin 'selvus' meaning wild or savage. |
| Senaany | One of the kauravas |
| Senthil Kumar | Lord Murugan, Always youth |
| Seras | Derived from the Latin word 'serere,' meaning to sow or plant, often associated with fertility. |
| Seshanand | Lord Vishnu, Beloved of sesh |
| Sesu | Snake, Venkateswara |
| Sethu Lakshmi | Goddess Lakshmi, Worth |
| Setukrute | Builder of the bridge over ocean |
| Sewin | Sewin is a Welsh name meaning 'little river' or 'stream', derived from the Old Welsh word 'sawyn'. |
| Shaantiv | One who is peaceful and calm in nature. |
| Shaast | Ruler, One who commands |
| Shaasti | Command, Royal authority, Hymn, Lord Murugan, Another name for Durga |
| Shabast | Armoured, Protected |
| Shadananan | Lord Subramanyan |
| Shagdav | Shagdav is a Mongolian name meaning 'bringer of good fortune' or 'auspicious one'. |
| Shailaj | Daughter of the mountains |
| Shainin | Peaceful, Restrained |
| Shajaneesh | Shajaneesh is a Sanskrit name meaning 'Victory of the Lord' or 'Triumphant Lord'. |
| Shajunan | Shajunan is a variant of the name Shahjahan, meaning 'world conqueror' or 'conqueror of the world'. |
| Shakith | Shakith is a variant of Shakitha, meaning 'blessed' or 'fortunate' in Sanskrit, derived from the word 'shak' meaning 'good fortune'. |
| Shakthidhar | Lord Shiva, The Lord Subramanian |
| Shakunth | Derived from a bird, meaning auspicious. |
| Shakya | Lord Buddha, Energy circle or a form of chakra |
| Shalivahan | Name of a famous king |
| Shamath | Quiet, Tranquillity, A counseller, Residing in peace, Peaceful, Calm |
| Shamen | Holy Man, Happy, Auspicious, Security, Wealthy |
| Shamijith | Shamijith means 'peaceful victory' or 'victory of peace' in Malayalam, a language spoken in southern India. |
| Shammad | One who has conquered his ego |